药学学报, 2019, 54(1): 73-81
引用本文:
刘洁, 肖红斌. 基于色谱技术的中药药效物质研究进展[J]. 药学学报, 2019, 54(1): 73-81.
LIU Jie, XIAO Hong-bin. Research progress on pharmacodynamic substances of Chinese Medicine based on chromatographic techniques[J]. Acta Pharmaceutica Sinica, 2019, 54(1): 73-81.

基于色谱技术的中药药效物质研究进展
刘洁1,2, 肖红斌2
1. 北京中医药大学北京中医药研究院, 北京 100029;
2. 北京中医药大学中药分析与转化研究中心, 北京 100029
摘要:
中药药效物质的阐明是中药现代化的基础,现代色谱技术在中药药效物质研究中发挥着重要作用,极大推动了中药药效物质的阐明。本文结合作者研究工作,主要从分析检测、分离制备及筛选三个层面综述基于色谱技术的中药药效物质研究进展。
关键词:    色谱      药效物质      中药      检测      制备      筛选     
Research progress on pharmacodynamic substances of Chinese Medicine based on chromatographic techniques
LIU Jie1,2, XIAO Hong-bin2
1. Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China;
2. Research Center for Chinese Medicine Analysis and Transformation, Beijing University of Chinese Medicine, Beijing 100029, China
Abstract:
To modernize traditional Chinese medicine, its pharmacodynamic substances should be elucidated firstly. Modern chromatographic technologies play an important role in the clarification of the pharmacodynamic substances of Chinese medicine. In this paper, the advancement and application of current chromatographic techniques in the pharmacodynamic substances of Chinese medicines were reviewed from the aspects of detection, preparation and screening methods.
Key words:    chromatographic    pharmacodynamic substance    Chinese medicine    detection    preparation    screening   
收稿日期: 2018-08-14
DOI: 10.16438/j.0513-4870.2018-0740
基金项目: 国家重大专项新药创制(2018ZX09201008-001);国家自然科学基金项目(81573839,81774155,81803703);中国博士后科学基金面上项目(2018M630119).
通讯作者: 肖红斌,Tel/Fax:86-10-64286490,E-mail:hbxiao69@163.com
Email: hbxiao69@163.com
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