Acta Pharmaceutica Sinica B


2012 Vol. 2 No. 2, 2012-04-25

Editor Profile and Editorial

Editor Profile: Guest Editor and Executive Editor-in-Chief of Special Issue "Drug Metabolism and Transport”

Xinxin Ding

2012 , 2(2): 91-91   doi:

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Cover story

Ai-Ming Yu and Yu-Zhuo Pan

2012 , 2(2): 92-92   doi:

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Editorial

Xinxin Ding

2012 , 2(2): 92-92   doi:

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Reviews

Original Articles

Cytochrome P450 2C24: expression, tissue distribution, highthroughput assay, and pharmacological inhibition

Jun Yang, Melissa A. VanAlstine, James G. Phillips, Mark P. Wentland, Lindsay B. Hough

2012 , 2(2): 137-145   doi:

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Epigenetic regulation of developmental expression of Cyp2d genes in mouse liver

Ye Li, Xiao-bo Zhong

2012 , 2(2): 146-158   doi:

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Characterization of ornidazole metabolites in human bile after intraveneous doses by ultraperformance liquid chromatography/ quadrupole time-of-flight mass spectrometry

Jiangbo Du, Pan Deng, Xiaoyan Chen, Haidong Wang, Tiangeng You, Dafang Zhong

2012 , 2(2): 159-167   doi:

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Determination of the enantioselectivity of six chiral aryloxy aminopropanol drugs transport across Caco-2 cell monolayers

Ye Tian, Ying He, Haihong Hu, Lu Wang, Su Zeng

2012 , 2(2): 168-173   doi:

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Biliary excretion and enterohepatic circulation of thienorphine and its glucuronide conjugate in rats

Jingting Deng, Xiaomei Zhuang, Guolin Shen, Hua Li, Zehui Gong

2012 , 2(2): 174-180   doi:

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In vitro screening of reversible and time-dependent inhibition on CYP3A by TM208 and TM209 in rat liver microsomes

Miaoran Ning, Liang Li, Jian Li, Zaiquan Li, Runtao Li, Tianyan Zhou, Wei Lu

2012 , 2(2): 181-187   doi:

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HPLC–MS and HPLC–MS/MS analysis of seven active constituents of Xiao-Xu-Ming decoction and application to a pharmacokinetic study after oral administration to rat

Yilin Wang, Chunguang Ding, Caisheng Wu, Kehe Du, Jinlan Zhang, Hailin Qin, Jinfeng Hou, Guanhua Du

2012 , 2(2): 188-197   doi:

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Changes in the pharmacokinetics of glibenclamide in rats with streptozotocin-induced diabetes mellitus

Yuqing Li, Yuhui Wei, Fan Zhang, Dan Wang, Xinan Wu

2012 , 2(2): 198-204   doi:

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Simultaneous determination of ivabradine and N-desmethylivabradine in human plasma and urine using a LC-MS/ MS method: application to a pharmacokinetic study

Chengtao Lu, Yanyan Jia, Jing Yang, Xin Jin, Ying Song, Wenxing Liu, Yi Ding, Xiaoli Sun, Aidong Wen

2012 , 2(2): 205-212   doi:

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Prodrug design, synthesis and pharmacokinetic evaluation of (30R, 40R)-3-hydroxymethyl-4-methyl-30, 40-di-O-(S)-camphanoyl-( +)-cis-khellactone

Huanfang Guo, Xiaomei Zhuang, Keduo Qian, Lianqi Sun, Xiaofeng Wang, Hua Li, Kuohsiung Lee, Lan Xie

2012 , 2(2): 213-219   doi:

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Screening and confirmation methods of the major urinary metabolite of finasteride–carboxy-finasteride by liquid chromatography– mass spectrometry and liquid chromatography– tandem mass spectrometry

Jianli Zhang

2012 , 2(2): 220-226   doi:

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