2016 Hot Papers* in ActaPharmaceuticaSinica B


Discovery of direct inhibitors of Keap1–Nrf2 protein–protein interaction as potential therapeutic and preventive agents.

Review Article

Dhulfiqar Ali Abed, Melanie Goldstein, Haifa Albanyan, Huijuan Jin, Longqin Hu

2015; 5(4):285-299.


Novel coumarin–benzimidazole derivatives as antioxidants and safer anti-inflammatory agents.

Review Article

RadhaKrishanArora, NavneetKaur, YogitaBansal, GulshanBansal

2014; 4(5): 368-375.


Can formulation and drug delivery reduce attrition during drug discovery and development—review of feasibility, benefits and challenges.

Review Article

S Basavaraj, Guru V. Betageri

2014; 4(1): 3-17.


Cancer metastases: challenges and opportunities.

Review Article

Xiangming Guan

2015; 5(5):402-418.


4-Hydroxybenzyl-substituted amino acid derivatives from Gastrodia elata.

Original Research Article

QinglanGuo, Yanan Wang, Sheng Lin, Chenggen Zhu, Minghua Chen, Zhibo Jiang, ChengboXu, Dan Zhang, Huailing Wei, Jiangong Shi

2015; 5(4):350-357


Mechanisms of resistance to EGFR tyrosine kinase inhibitors.

Review Article

Lihua Huang, Liwu Fu

2015; 5(5):390-401.


Fundamental aspects of solid dispersion technology for poorly soluble drugs.

Review Article

Yanbin Huang, Wei-Guo Dai

2014; 4(1):18-25


Smart polymers for the controlled delivery of drugs – a concise overview.

Review Article

Honey Priya James, Rijo John, Anju Alex, K.R. Anoop

2014; 4(2):120-127.


Bile acid signaling and biliary functions.

Review Article

Hannah Jones, Gianfranco Alpini, Heather Francis

2015; 5(2): 123-128.


Insoluble drug delivery strategies: review of recent advances and business prospects.

Review Article

SandeepKalepu, VijaykumarNekkanti

2015; 5(5): 442-453


Nanocarrier-mediated co-delivery of chemotherapeutic drugs and gene agents for cancer treatment.

Review Article

Lin Kang, ZhonggaoGao, Wei Huang, Mingji Jin, Qiming Wang

2015; 5(3):169-175.


HIF-1α pathway: role, regulation and intervention for cancer therapy.

Review Article

Georgina N. Masoud, Wei Li

2015; 5(5): 378-389.


New small-molecule drug design strategies for fighting resistant influenza A.

Review Article

ZuyuanShen, Kaiyan Lou, Wei Wang

2015; 5(5):419-430.


Alectinib: a novel second generation anaplastic lymphoma kinase (ALK) inhibitor for overcoming clinically-acquired resistance.

Review Article

Zilan Song, Meining Wang, Ao Zhang

2015; 5(1): 34-37.


Near-infrared fluorescent probes for imaging of amyloid plaques in Alzheimer’s disease.

Review Article

Hongjuan Tong, Kaiyan Lou, Wei Wang

2015; 5(1): 25-33.


Brain tumor-targeted drug delivery strategies.

Review Article

Xiaoli Wei, Xishan Chen, Man Ying, Weiyue Lu

2014; 4(3):193-201.


The antitumor effect of tanshinone IIA on anti-proliferation and decreasing VEGF/VEGFR2 expression on the human non-small cell lung cancer A549 cell line.

Original Research Article

Jun Xie, Jiahui Liu, Heng Liu, Shihui Liang, Meigui Lin, YueyuGu, Taoli Liu, Dongmei Wang, HuiGe, Sui-lin Mo

2015; 5(6): 554-563.


Emerging role of microRNAs in lipid metabolism.

Review Article

Zhihong Yang, Tyler Cappello, Li Wang

2015; 5(2): 145-150.


Glucosylated caffeoylquinic acid derivatives from the flower buds of Lonicera japonica.

Original Research Article

Yang Yu, Zhibo Jiang, Weixia Song, Yongchun Yang, Yuhuan Li, Jiandong Jiang, Jiangong Shi

2015; 5(3): 210-214.


Hydrogen sulfide prodrugs—a review

Review Article

YueqinZheng, XingyueJi, KailiJi, Binghe Wang

2015; 5(5): 367-377.

                   *High cited papers in 2016, published in 2014-2015, according to the records in Web of Science