干姜中两个新的二苯庚烷类化合物

Two new diarylheptane derivatives from Rhizoma Zingiberis

摘要: 运用Diaion HP-20、MCI Gel CHP-20、ODS、硅胶、反相半制备高效液相等多种色谱分离技术，从干姜中分离得到2个新的二苯庚烷类化合物，通过MS、UV、IR和NMR等波谱技术鉴定其结构分别为：3-酮-5R-乙氧基-1-（3-甲氧基-4-羟基苯基）-7-（3，4-二羟基苯基）庚烷（1）和3-酮-5R-乙氧基-1-（3-甲氧基-4-羟基苯基）-7-（3-甲氧基-4，5-二羟基苯基）庚烷（2），化合物1、2均为新化合物。

Abstract: Two new diarylheptane derivatives were isolated from Rhizoma Zingiberis by Diaion HP-20, MCI Gel CHP-20, ODS, silica gel column and reverse phase semi-prepared high performance liquid chromatography. Their structures were elucidated by spectrum technology (MS, UV, IR, NMR), which were identified as 3-keto-5R-ethoxy-1-(3-methoxy-4-hydroxyphenyl)-7-(3,4-dihydroxyphenyl)heptane (1) and 3-keto-5R-ethoxy-1-(3-methoxy-4-hydroxyphenyl)-7-(3-methoxy-4,5-dihydroxyphenyl)heptane (2). Compounds 1 and 2 are new compounds.