任玉洁, 张硕, 魏粉菊, 刘新泳, 展鹏. 埃博拉病毒抑制剂研究新进展J. 药学学报, 2020,55(4): 694-702. doi: 10.16438/j.0513-4870.2019-0859
引用本文: 任玉洁, 张硕, 魏粉菊, 刘新泳, 展鹏. 埃博拉病毒抑制剂研究新进展J. 药学学报, 2020,55(4): 694-702. doi: 10.16438/j.0513-4870.2019-0859
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REN Yu-jie, ZHANG Shuo, WEI Fen-ju, LIU Xin-yong, ZHAN Peng. Recent advances in the discovery and development of Ebola virus inhibitorsJ. Acta Pharmaceutica Sinica, 2020,55(4): 694-702. doi: 10.16438/j.0513-4870.2019-0859
Citation: REN Yu-jie, ZHANG Shuo, WEI Fen-ju, LIU Xin-yong, ZHAN Peng. Recent advances in the discovery and development of Ebola virus inhibitorsJ. Acta Pharmaceutica Sinica, 2020,55(4): 694-702. doi: 10.16438/j.0513-4870.2019-0859
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埃博拉病毒抑制剂研究新进展

Recent advances in the discovery and development of Ebola virus inhibitors

    摘要
  • 摘要: 埃博拉病毒具有高度传染性，可引起严重出血热的暴发，致死率高达90%。目前没有疫苗、生物制剂或特异性的小分子化合物类防治药物。近几年，大量文献报道了埃博拉病毒抑制剂，本文综述了该领域的研究新进展。

     

    Abstract: Ebola virus is extremely virulent and highly contagious. Ebola virus causes outbreaks of severe hemorrhagic fever, with human mortality rates of up to 90%. There is currently no preventive or therapeutic treatment in the form of vaccines, biological or small molecular agents. Currently, a lot of anti-Ebola virus agents have been reported. Here, we review the latest advances in this field.

     

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