姜皮中一个新的二苯庚烷二聚体

A new diarylheptane dimer from Zingiber officinale peel

摘要: 运用MCI Gel CHP-20、Sephadex LH-20、ODS、半制备高效液相等色谱技术，从姜皮正丁醇部位中分离得到3个二苯庚烷类化合物，通过MS和NMR波谱学技术鉴定其结构为：（2S，2'S，3R，3'R，4R，4'R，6R，6'R）-6，6'-bis （（S）-1-hydroxy-2-（4-hydroxyphenyl）ethyl）-2，2'-bis （4-hydroxy-3-methoxyphenyl）octahydro-2H，2'H-3，3'-bipyran-4，4'-diol （1）、（E）-7-（4-hydroxy-3-methoxyphenyl）-1-（4-hydroxyphenyl）hept-4-en-3-one （2）和alpinin B （3），化合物1为新化合物，化合物2、3为首次从姜皮中分离得到。

Abstract: Three diarylheptanoids were isolated from the n-butanol fraction of Zingiber officinale peel by MCI Gel CHP-20, Sephadex LH-20, ODS and semipreparative high performance liquid chromatography. Their structures were identified by MS and NMR spectroscopy techniques:(2S,2'S,3R,3'R,4R,4'R,6R,6'R)-6,6'-bis((S)-1-hydroxy-2-(4-hydroxyphenyl)ethyl)-2,2'-bis(4-hydroxy-3-methoxyphenyl)octahydro-2H,2'H-3,3'-bipyran-4,4'-diol (1), (E)-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)hept-4-en-3-one (2), and alpinin B (3). Compound 1 is a new compound, and compounds 2-3 were obtained from Zingiber officinale peel for the first time.