思茅松松脂中一个新的二萜酸

A new diterpenoid acid from the rosin of Pinus kesiya var. langbianensis (A.Chev.) Gaussen ex Bui

摘要: 运用MCI Gel、Sephadex LH-20、ODS和硅胶等柱色谱, 结合半制备液相、TLC等分离方法, 从思茅松松脂的95%乙醇部位分离纯化得到7个化合物。运用现代波谱学方法(1D、2D NMR、UV、IR、MS等) 对所分离得到的化合物进行结构鉴定, 并运用计算ECD的方法确定了新化合物的绝对构型。其中, 化合物1为新化合物, 化合物2、5~7为首次从思茅松中分离得到。

Abstract: One undescribed diterpenoid acid and six compounds were isolated from the 95% ethanol fraction of Pinus kesiya var. langbianensis (A.Chev.) Gaussen ex Bui resin by using various chromatographic methods, including MCI Gel, Sephadex LH-20, ODS, silica gel and semi-preparative HPLC. The planar structures were identified by spectroscopy methods (1D, 2D NMR, UV, IR, MS, etc.), and the absolute configuration of the new compound was determined by ECD calculation. Compound 1 is a new compound, and compounds 2, 5-7 were isolated from Pinus kesiya var. langbianensis (A.Chev.) Gaussen ex Bui for the first time.