杜仲中的一个新环烯醚萜类化合物

A new iridoid from Eucommia ulmoides

摘要: 利用硅胶、Sephadex LH-20和Toyopearl HW-40C等柱色谱及半制备液相等分离纯化方法, 从杜仲中分离得到11个化合物。运用现代波谱学方法确定化合物的结构, 分别鉴定为neoeucommiate A (1)、(7S, 8R)-dihydrodehydrodiconiferyl alcohol (2)、urolignoside (3)、ficusal (4)、tiruneesiin (5)、glochidioboside (6)、forsythialansides B (7)、ecdysanol B (8)、(+)-syringaresinol-4-O-β-D-glucopyranoside (9)、(+)-pinoresinol-4-O-6ʹʹ-O-vanilloyl-β-D-glucopyranoside (10) 和samsesquinoside (11)。其中化合物1为新化合物, 化合物3~7、10、11为首次从杜仲中分离得到。

Abstract: Eleven compounds were isolated from Eucommia ulmoides by silica gel, Sephadex LH-20, HW-40C column chromatography and semi-preparative HPLC. Their structures were identified by modern spectroscopic methods as neoeucommiate A (1), (7S, 8R)-dihydrodehydrodiconiferyl alcohol (2), urolignoside (3), ficusal (4), tiruneesiin (5), glochidioboside (6), forsythialansides B (7), ecdysanol B (8), (+)-syringaresinol-4-O-β-D-glucopyranoside (9), (+)-pinoresinol 4-O-6ʹʹ-O-vanilloyl-β-D-glucopyranoside (10), samsesquinoside (11). Compound 1 is a new compound, compounds 3-7, 10 and 11 were isolated from Eucommia ulmoides for the first time.