Abstract: Artificial intelligence (AI) has progressively integrated into various fields and plays a significant role. With the advent of China's aging population era and the growing public demand for healthcare, the application of AI in the field of clinical pharmacy has garnered considerable attention. Clinical pharmacy is crucial for ensuring the safety and effectiveness of clinical medication use by optimizing drug therapy and preventing medication errors. Due to its advantages, such as powerful data processing and analysis capabilities, and robust model-based predictive abilities, AI holds broad application prospects in the field of clinical pharmacy. This article introduces the current progress in AI applications within clinical pharmacy, focusing on its use in enhancing drug efficacy and safety. These applications include: assisting drug selection, optimizing dosage and administration timing, providing intelligent pharmaceutical services, predicting drug-drug interactions, pharmacovigilance, and preventing medication errors. Building on a review of current advancements, the article also discusses the challenges faced in implementing these AI applications. It proposes potential solutions, aiming to provide a reference for subsequent research and relevant practitioners.