铁包金中一个新的色原酮衍生物

A new chromone derivative from Berchemia lineata

摘要:
利用正相硅胶、反相硅胶和HPLC等色谱手段进行化学成分的分离, 从铁包金乙酸乙酯提取物中分离得到9个化合物。化合物经波谱分析鉴定为5-hydroxy-7-(2'-hydroxypropyl)-2-methyl-chromone (1)、(−)-(1'R, 2'S)- erythro-5-hydroxy-7-(1', 2'-dihydroxypropyl)-2-methyl-chromone (2)、柚皮素 (3)、圣草酚 (4)、(+)-香橙素 (5)、(+)-花旗松素 (6)、(+)-儿茶素 (7)、(+)-表没食子儿茶素 (8) 和槲皮素 (9)。其中化合物2为新的色原酮衍生物, 化合物1为首次从该属植物中分离得到。化合物3～9为黄酮类化合物, 为首次从该种植物中分离得到。

Abstract:
To study the chemical constituents from the root of Berchemia lineata (L.) DC., nine compounds were isolated from the EtOAc extract by using silica gel, RP-C18 silica gel column chromatography and preparative HPLC. Based on the spectroscopic analysis, their structures were identified as 5-hydroxy-7-(2'-hydroxypropyl)- 2-methyl-chromone (1), (−)-(1'R, 2'S)-erythro-5-hydroxy-7-(1', 2'-dihydroxypropyl)-2-methyl-chromone (2), naringenin (3), eriodictyol (4), (+)-aromadendrin (5), (+)-taxifolin (6), (+)-catechin (7), (+)-epigallocatechin (8) and quercetin (9). Among them, compound 2 is a new chromone derivative. Compound 1 is a known chromone derivative and isolated from this genus for the first time. Compounds 3−9 are known flavonoids and isolated from this plant for the first time.