刘志煜, 吴向荣, 何煦昌. 16-(m-氯苯氧基)-17,18,19,20失四碳前列腺素F2α的全合成J. 药学学报, 1985, 20(2): 140-142.
引用本文: 刘志煜, 吴向荣, 何煦昌. 16-(m-氯苯氧基)-17,18,19,20失四碳前列腺素F2α的全合成J. 药学学报, 1985, 20(2): 140-142.
shu
LIU Zhi-Yu, WU Xiang-Rong , HE Xu-Chang, . SYNTHESIS OF l6-(m-CHLOROPHENOXY)-17, 18, 19, 20-TETRANOR-PROSTAGLANDIN F2αJ. Acta Pharmaceutica Sinica, 1985, 20(2): 140-142.
Citation: LIU Zhi-Yu, WU Xiang-Rong , HE Xu-Chang, . SYNTHESIS OF l6-(m-CHLOROPHENOXY)-17, 18, 19, 20-TETRANOR-PROSTAGLANDIN F2αJ. Acta Pharmaceutica Sinica, 1985, 20(2): 140-142.
shu

16-(m-氯苯氧基)-17,18,19,20失四碳前列腺素F2α的全合成

SYNTHESIS OF l6-(m-CHLOROPHENOXY)-17, 18, 19, 20-TETRANOR-PROSTAGLANDIN F2α

    摘要
  • Abstract: A simplified synthetic method for compound (1) was described. Both α,β-unsaturated ketone and y-lactone of (4)b were reduced with Dibal simultaneously to corresponding allylic hydroxy group and γ-lactol in good yield. Without protecting the hydroxy group, the mixture (6) was transformed to the target compound (1) by the known method.

     

    • HTML全文
    • 参考文献(0)
    • 相关文章
    • 施引文献
  • 资源附件(0)

/

返回文章
返回