黄培强, BRouot, RWylde, BCastro. 一个新型α1-去甲肾上腺素受体的光亲和放射性碘探针的母体化合物的合成J. 药学学报, 1992, 27(11): 864-866.
引用本文: 黄培强, BRouot, RWylde, BCastro. 一个新型α1-去甲肾上腺素受体的光亲和放射性碘探针的母体化合物的合成J. 药学学报, 1992, 27(11): 864-866.
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PQ Huang, B Rouot, R Wylde, B Castro. SYNTHESIS OF THE KEY INTERMEDIATE FOR A NEW RADIOIODINATED PHOTOAFFINITY PROBE FOR α1-ADRENERGIC RECEPTORJ. Acta Pharmaceutica Sinica, 1992, 27(11): 864-866.
Citation: PQ Huang, B Rouot, R Wylde, B Castro. SYNTHESIS OF THE KEY INTERMEDIATE FOR A NEW RADIOIODINATED PHOTOAFFINITY PROBE FOR α1-ADRENERGIC RECEPTORJ. Acta Pharmaceutica Sinica, 1992, 27(11): 864-866.
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一个新型α1-去甲肾上腺素受体的光亲和放射性碘探针的母体化合物的合成

SYNTHESIS OF THE KEY INTERMEDIATE FOR A NEW RADIOIODINATED PHOTOAFFINITY PROBE FOR α1-ADRENERGIC RECEPTOR

    摘要
  • Abstract: A new and high-yielding procedure was described for the synthesis of 4-amino-6,7-dimethoxy-24-4 (4-aminophenyl) butanoyl-1-piperazinyl-quinazoline Ⅶ, the key intermedi-ate for the newly designed potential α1-AR affinity/photoaffinity probes Ⅷa/Ⅸa.

     

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