博落回果实中有效成份的研究

STUDIES ON THE ACTIVE PRINCIPLES OF THE FRUITS OF MACLEAYA CORDATA (WILLD.) R. Br.

摘要: 从博落回果实中分得五种生物碱,经理化数据分析证实为:血根碱Sanguinarine,C₂₀H₁₅O₅N白屈菜红碱Chelerythrine.C₂₁H₁₉O₅N原阿片碱Protopine,C₂₀H₁₉O₅Nα-别隐品碱α-Al-locryptopine,C₂₁H₂₃O₆N及β-别隐品碱β-Allocryptopine,C₂₁H₂₃O₅H前两种化合物经氨性乙醇重结晶得乙氧基血根碱和乙氧基白屈菜红碱,药理和临床试验表明,有较好的抗菌消炎作用,尤其对宫颈炎疗效显著,并已通过鉴定。

Abstract: Five alkaloids were isolated from the fruits of Macleaya cordata (Willd.) R. Br. They have been identified as Sanguinarine, Ghelerythrine, Protopine, α-Allocryptopine and β-Allocryptopine. In pharmacological studies and clinical trials the former two compounds showed comparatively good antibacterial and antiphlogistical effects.