蜜环菌菌丝体化学成分的研究——Ⅴ.蜜环菌辛素和蜜环菌壬素的分离与鉴定

STUDIES ON THE CHEMICAL CONSTITUENTS OF ARMILLARIA MELLEA MYCELIUM Ⅴ. ISOLATION AND CHARACTERIZATION OF ARMILLARILIN AND ARMILLARININ

摘要: 从人工液体发酵培养的蜜环菌Armillaria mellea(Vahl.ex Fr.)Quel.菌丝体的石油醚提取物中,经硅胶柱层析,低压柱层析和制备性薄层层析分离得到两个新的原伊鲁烷型倍半萜芳香酸酯类化合物。命名为蜜环菌辛素(armillarilin)和蜜环菌壬素(armillarinia),根据光谱(UV,IR,¹HNMR,¹³CNMR和MS)分析,推定它们的化学结构分别为Ⅰ和Ⅱ。

Abstract: Two new protoilludane sesquiterpenoid aromatic esters, armillarilin C₂₄H₃₀O₇, mp 179/180℃, α_D¹⁴+162 (c 0.097, CHCl₃ and armillarinin C₂₄H₂₉O₇ Cl, mp 152～155℃, α_D¹⁷+153.6 (c 0.09, CHCl₃), have been isolated from the artificially cultured rayeeliura of Armillaria mellea (Vahl. ex Fr.) Quel (Wricholoraetaceae).On the basis of spectral (UV, IR ¹HNMR,¹³CNMR and MS) analysis their structures were identified as Ⅰ and Ⅱ, respectively.