杨梅树皮中一个新的二苯基庚烷类化合物

A new cyclic diarylheptanoid from the bark of Myrica rubra

摘要: 采用正相硅胶、Sephadex LH-20和制备液相等多种色谱方法从杨梅树皮甲醇提取物中得到14个化合物, 并通过化合物的理化性质和UV、IR、NMR、MS等波谱数据进行结构鉴定, 得到二苯基庚烷类化合物4个、黄酮类化合物3个、三萜及甾醇类化合物7个, 它们分别是: 3, 5-二甲氧基-4-羟基杨梅醇 (1)、杨梅醇 (2)、杨梅酮 (3)、myricanol 11-sulfate (4)、杨梅苷 (5)、槲皮素 (6)、槲皮苷 (7)、柽柳醇 (8)、熊果醇 (9)、熊果酸 (10)、蒲公英赛醇 (11)、杨梅萜二醇 (12)、β-谷甾醇 (13) 和β-胡萝卜苷 (14).其中1为新化合物, 化合物8和9为首次从该属植物中分离得到.

Abstract: To study the chemical constituents from the bark of Myrica rubra, fourteen compounds were isolated from the methanolic extract using various chromatographic techniques, including silica gel, Sephadex LH-20 and preparative HPLC. Their structures were identified on the basis of chemical properties and spectroscopic data, as 3, 5-dimethoxy-4-hydroxymyricanol (1), myricanol (2), myricanone (3), myricanol 11- sulfate (4), myricitrin (5), quercetin (6), quercetin-3-rhamnoside (7), tamarixol (8), uvaol (9), ursolic acid (10), taraxerol (11), myricadiol (12), β-sitosterol (13) and β-daucosterol (14). Among them, compound 1 is a new compound, named as 3, 5-dimethoxy-4-hydroxymyricanol, compounds 8, 9 were isolated from the genus Myrica for the first time.