黄杉化学成分的研究

STUDIES ON THE CHEMICAL CONSTITUENTS OF PSEUDOTSUGA SINENSIS

摘要: 目的研究黄杉的化学成分。方法用色谱方法分离黄杉化学成分,用波谱技术(IR,UV,MS,1D和2D-NMR)鉴定结构。结果从黄杉树皮中分离得到6个化合物,分别鉴定为5,7,4′-trihydroxy-6-methylflavanone (poriol, I), 3,5,7,3′,4′-pentahydroxyflavonone (quercetin, II), 5,7,3′,5′-tetrahydroxy-6-methylflavanone (III), 5,7,3′,5′-tetrahydroxyflavanone (IV), 3,5,7,3′,5′-pentahydroxyflavanone (V)和5-hydroxy-6-methylchromone-7-O-β-D-glucopyranoside (VI)。结论III,VI为新化合物,所得6个化合物均为首次从该属植物中分得。

Abstract: AIMTo study the chemical constituents of Pseudotsuga sinensis Dode (Pinaceae). METHODS To separate the constituents of P.sinensis by using various kinds of chromatography and identify their structures on the basis of spectral analysis. RESULTSSix compounds were isolated from P. sinensis. Their structures were established as 5,7,4′-trihydroxy-6-methylflavanone (poriol, I), 3,5,7,3′,4′-pentahydroxyflavonone (quercetin, II), 5,7,3′,5′-tetrahydroxy-6-methylflavanone (III), 5,7,3′,5′-tetrahydroxyflavanone (IV), 3,5,7,3′,5′-pentahydroxyflavanone (V) and 5-hydroxy-6-methylchromone-7-O-β-D-glucopyranoside (VI) based on the analysis of spectral data of IR, UV, MS, 1D and 2D-NMR. CONCLUSIONCompounds III and VI are new compounds. All of six compounds were isolated from this plant for the first time.