哺乳期避孕药ST-1435衍生物的合成
SYNTHESIS OF ST-1435 DERIVATIVES AS CONTRACEPTIVE FOR LACTATING WOMEN
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Abstract: Four new ST- 1435 derivatives 4~ 7 were synthesized. Both 4 and 5 are mixture of Z- and E- isomers. 4 was separated into Z- and E- isomers by spinning TLC. Their binding ability to progesterone receptor was examined and found to be less than ST- 1435.
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