Abstract: Nitration of cis-β-(2-furyl) acrylic acid afforded the corresponding cis-β-(5-nitro-furyl), acrylic acid. It was readily converted to cis-β-(5-nitro-2-furyl)-N-isopropyl-acrylamide by amination with isopropylamine through the mixed anhydride method.The biological activity of this cis-isomer was examined in laboratory animals against experimental schistosomiasis and was shown to possess activity similar to that already reported for the trans-isomer.