碳糊电极阳极伏安法测定秋水仙碱

MEASUREMENT OF COLCHICINE BY ANODIC VOLTAMMETRY WITH CARBON PASTE ELECTRODE

摘要: 在0.05mol·L^-1H₂SO₄介质中,用碳糊电极(石墨粉:液体石蜡油=1.5∶1)阳极扫描伏安法测定秋水仙碱,检测限1×10^-7mol·L^-1,检测线性范围4.0×10^-7～1×10^-3mol·L^-1,氧化时出现两个氧化峰,峰电位分别为1.07V和1.33VvsSCE,峰电位随pH值升高而正移。对原料和片剂进行了测定,均获得满意的结果。

Abstract: Colchicine is determined by anodic voltammetry using a carbon paste electrode (graphite powder:paraffin liquid=1.5:1) in 0.05 mol·L^-1 H₂SO₄, with a linear range of 4.0×10^-7～1.0×10 ^-3 mol·L^-1, detection limit 1×10^-7mol·L^-1. Two waves at 1.07 and 1.33 V vs SCE were observed in the anodic scan, peak potential is increased with pH. The raw material and tablets of colchicine have been analysed with good results.