柴胡皂甙q及其甙元的结构鉴定

ISOLATION AND IDENTIFICATION OF SAIKOGENIN Q AND SAIKOSAPONIN Q FROM BUPLEUM SMITHII WOLFF VAR PARVIFOLIUM SHAN ET Y LI

摘要: 从小叶黑柴胡(Bupleurum smithii Wolffvar;parvifolium ShanetY.Li)的根中得到3个化合物,柴胡皂甙元A和Q及柴胡皂甙q。柴胡皂甙元Q和柴胡皂甙q为新化合物,根据理化性质和波谱分析,确定其结构分别为齐墩果烷-11,13(18)-二烯-3β,16β,23,28,30-五醇和3β,16β,23,28,3O-五羟基齐墩果烷-11,13(18)-二烯-3-O-β-D-吡喃葡萄糖基(1→6)-α-L-吡喃鼠李糖基(1→4)-β-D-吡喃葡萄糖甙。

Abstract: From the dried rhizome of Bupleurm smithii Wolff var.parvifolium Shan et Y.Li collected in Datong County,Qinghai province,China,a new saponin and a sapogenin along with aknown sapogenin(saikogenin A).(1)were isolated and their structures were elucidated on the basisof chemical and spectroscopic evidence.The new saponin,saikosaponin q(3) was identified as 3β,16β,23,28.30-pentahydroxyoleana-11,13(18)-diene-3-O-β-D-glucopyranosyl-(1→6)-α-L-rhamnopyranasyl-(1→4)-β-D-glucopyranoside.The new sapogenin　2)saikogenin Q,wasidentified as oleana-11,13(18)-diene-3β,16β,23,28,30-pentol.