红芽大戟化学成分研究

Studies on the chemical constituents of Knoxia corymbosa

摘要: 目的研究茜草科植物红芽大戟(Knoxia corymbosa Willd．)的化学成分。方法利用硅胶、聚酰胺等色谱技术分离纯化，根据化合物的理化性质和光谱数据进行鉴定。结果从红芽大戟的正丁醇萃取部分分离得到4个黄酮醇苷成分，分别鉴定为:槲皮素-7-O-α-L-阿拉伯糖-3-O-β-D-6″-乙酰基吡喃葡糖苷(quercetin-7- O-α-L-arabinosyl-3-O-β-D-6″-acetylglucopyranoside,1)；山奈酚-7-O-α-L-阿拉伯糖-3-O-β-D-吡喃葡糖苷(kaempferol-7-O-α-L-arabinosyl-3-O-β-D-glucopyranoside,2)；槲皮素-3-O-β-D-吡喃葡糖苷(quercetin-3-O-β-D-glucopyranoside,3); 槲皮素-3-O-β-D-6″-乙酰基吡喃葡糖苷(quercetin-3-O-β-D-6″-acetylglucopyranoside,4)。结论化合物1为新化合物，其余均为首次从该种植物分到。

Abstract: AimTo study the chemical constituents of Knoxia corymbosa Willd. Methods Chromatography was used to isolate and purify the chemical constituents， their structures were identified by spectral analysis． ResultsFour flavonol glycosides were identified as quercetin-7-O-α-L-arabinosyl-3-O-β-D-6″-acetylglucopyranoside (1)， kaempferol-7-O-α-L-arabinosyl-3-O-β-D-glucopyranoside (2)， quercetin-3-O-β-D-glucopyranoside (3)， quercetin-3-O-β-D-6″-acetylglucopyranoside (4)． Conclusion Compound 1 is a new flavonol glycoside. The other flavonol glycosides were isolated from Knoxia corymbosa Willd for the first time．