鸡血藤的化学成分研究

STUDIES ON THE CHEMICAL CONSTITUENTS OF Spatholobus suberectus DUNN

摘要: 目的研究中药鸡血藤(Spatholobus suberectus Dunn)的化学成分。方法利用多种柱色谱方法进行分离纯化,根据光谱数据和化学方法进行结构鉴定。结果从鸡血藤70%乙醇浸膏的乙酸乙酯部分分离鉴定了8个化合物,分别是:密花豆素(1)、芒柄花素(2)、大豆苷元(3)、毛蕊异黄酮(4)、焦性粘液酸(5)、间苯三酚(6)、琥珀酸(7)、β-谷甾醇(8)。结论化合物1为7,3′,4′-三羟基-6-甲氧基二氢黄酮,是1个新化合物,命名为密花豆素,化合物4,5,6和7为首次从本属植物中得到。

Abstract: AIMTo study the chemical constituents of Spatholobus suberectus Dunn. METHODSThe constituents of Spatholobus suberectus were separated with various chromatographic techniques. The structures were elucidated by physico-chemical properties and spectral data. RESULTSEight compounds were isolated from Spatholobus suberectus Dunn. They were identified as: suberectin (1), formononetin (2), daidzein (3), calycosin (4), pyromucic acid (5), 1,3,5-benzenetriol (6), succinic acid (7) and β-sitosterol (8). CONCLUSIONSuberectin is a new compound and characterized as 7,3′,4′-trihydroxy-6-methoxy flavanone on the basis of chemical and spectral evidence. Compounds 4, 5, 6 and 7 were obtained from Spatholobus genus for the first time.