山楂叶化学成分研究

CHAMICAL CONSTITUENTS FROM THE LEAVES OF CRATAEGUS PINNATIFIDA BGE. VAR. MAJOR N.E.Br.

摘要: 目的　研究山楂(CrataeguspinnatifidaBge .varmajorN .E .Br.)叶中的化学成分。方法　用大孔树脂柱色谱、硅胶柱色谱和聚酰胺柱色谱等技术进行分离纯化,根据理化性质和光谱数据进行结构鉴定。结果　得到8个化合物,分别为山楂素I(1) ,槲皮素(2 ) ,3-O-β-D-吡喃葡糖槲皮素(3) ,3-O-β-D-吡喃半乳糖槲皮素(4) ,3-O-β-D-吡喃葡糖(6→1)-α-L-鼠李糖槲皮素(5 ) ,3-O-β-D-吡喃半乳糖(6→1)-α-L-鼠李糖槲皮素(6 ) ,山萘酚(7) ,7-O-α-L-鼠李糖-3-O-β-D-葡糖山萘酚(8)。结论　1为新化合物,8为首次从该属中分得

Abstract: AIM To study the chemical constituents in the leaves of Crataegus pinnatifida Bge.var.major N.E.Br.. METHODS Compounds were isolated by using porous resin, silica gel, polyamide chromatographic techniques etc. Their structures were elucidated by chemical and spectroscopic methods. RESULTS Eight compounds were identified as pinnatifin I (1), quercetin (2),3-O-β-D-glucopyranosyl quercetin (3),3-O-β-D-galacopyranosyl quercetin (4),3-O-β-D-glucopyranosyl (6→1)-α-L-rhamnosyl quercetin (5),3-O-β-D-galacopyranosyl (6→1)-α-L-rhamnosyl quercetin (6), kaempferol (7),7-O-β-D-rhamnosyl3-O-β-D-glucopyranosyl kaempferol (8). CONCLUSION Compound 1 is a new compound. Compound 8 was isolated from this plant for the first time.