中国红树植物角果木的化学成分

Chemical constituents from the mangrove plant Ceriops tagal

摘要: 目的研究中国红树植物角果木(Ceriops tagal)的次生代谢成分。方法用多种色谱技术进行分离纯化，根据理化性质和波谱数据进行结构鉴定。结果从中国红树植物角果木石油醚部分分离出9个化合物，并确定了它们的结构分别为：tagalsins A (1)，ent-5α-dolabr-4(18)-ene-15S,16-diol (2)，鲨烯(3)，白桦脂酸(4)，羽扇-20(29)-烯-3-酮-28-羧酸(5)，白桦脂醇(6)，羽扇-20(29)-烯-3-酮-28-醇(7)，β-谷甾醇(8)，阿魏酸二十六醇酯(9)。其中化合物1和2为dolabrane型二萜。结论化合物1为新化合物，2～9系首次从该种中分离得到。

Abstract: AimTo investigate the secondary metabolites of the mangrove plant Ceriops tagal. MethodsColumn chromatography techniques including HPLC were used for the separation and purification , and extensive spectral analysis including various 2D NMR spectra were employed for structure elucidation. ResultsNine compounds, namely, tagalsins A (1), ent-5α-dolabr-4(18)-ene-15S,16-diol (2), squalene (3), betulinic acid (4), lup-20(29)-en-3-on-28-oic acid (5), betulin (6), lup-20(29)-en-3-on-28-ol (7), β-sitosterol (8), n-hexacosanylferulate (9) were obtained. Of which 1 and 2 belong to dolabrane diterpene. ConclusionCompound 1 is a new compound, and 2 to 9 are isolated from this species for the first time.