岗松中的一个新黄酮醇苷类化合物

A new flavonol glycoside from Baeckea Frutescens L.

摘要: 为了研究岗松的化学成分，采用硅胶、聚酰胺柱层析色谱和重结晶的方法对化合物进行分离纯化，通过理化性质和波谱技术鉴定化合物结构。分离并鉴定了8个化合物：6，8-二甲基山柰酚-3-O-α-L-鼠李糖苷(1)、槲皮素(2)、槲皮素-3-O-α-L-鼠李糖苷(3)、杨梅素(4)、杨梅素-3-O-α-L-鼠李糖苷(5)、没食子酸(6)、熊果酸(7)和1,3-二羟基-2-(2′-甲基丙酰基)-5-甲氧基-6-甲基苯(8)。其中，化合物1为新黄酮醇苷类化合物，化合物2～7为首次从该植物中分离得到，化合物8为首次从植物中分离得到。

Abstract: To study the chemical constituents of the traditional Chinese herb Baeckea Frutescens L., a new flavonol glycoside, named 6,8-dimethylkaempferol-3-O-α-L-rhamnoside (1), together with seven known compounds: quercetin (2), quercetin-3-O-α-L-rhamnoside (3), myricetin (4), myricetin-3-O-α-L-rhamnoside (5), gallic acid (6), ursolic acid (7) and 1,3-dihydroxy-2-(2′-methoxylpropionyl)-5-methoxy-6-methylbenzene (8) were isolated by using silica gel column chromatography, polyamide column chromatography and recrytallization. Their structures were identified on the basis of physicochemical properties and spectroscopic analysis. Among them, compounds 2-7 were isolated from this plant for the first time and compound 8 was first isolated from plant.