黄毛忽木皂甙A的分离和结构测定

ISOLATON AND STRUCTURAL ELUCIDATON OF ARADECOSIDE A FROM THE ROOT OF ARALIA DECAISNEANA

摘要: 黄毛木(Aralia decaisneana Hance)为五加科木属植物。从其根的甲醇提取物中分离得到一个皂甙化合物(I),根据光谱(IR,¹HNMR,¹³CNMR,MS,Longrange ¹H-¹HCOSY和¹H-¹³cHETCOR)解析和化学反应(酸水解,乙酰化和碱水解)证明,化合物1的结构确定为3-O-β-D-吡喃木糖1→3)-β-D-吡喃葡萄糖(1→2)-β-D-吡喃葡萄糖-28-O-β-D-吡喃葡萄糖(1→6)-β-D-吡喃葡萄糖酯甙。该化合物是一个新的三萜皂甙,命名为黄毛木皂甙A(aradecoside A)。

Abstract: A new triterpenoid saponin,C₅₉H₉₆O₂₇ ,named Aradecoside A(I),was isolatedfrom the root of Aralia decaisneana Hance(Araliaceae).The determination of its structure was based onspectroscopic analysis( IR, ¹HNMR,¹³CNMR ,MS,Long-range ¹H-¹HCOSY or ¹H-¹³C HETCOR)of the natural compound and its derivatives,and characterized as 3-O-β-D-xylo-pyranosyl(1→3)- β-D-glucopyranosyl(1→2)-β-D-glucopyranosyl-oleanolic acid-28-O-β-D-glucopyranosyl(1→6)-β-D-glucoDyrandsyl ester.