李福林, 张其楷. 分子连接性在脂肪胺类神经节阻断剂定量构效关系中的应用J. 药学学报, 1982, 17(8): 592-596.
引用本文: 李福林, 张其楷. 分子连接性在脂肪胺类神经节阻断剂定量构效关系中的应用J. 药学学报, 1982, 17(8): 592-596.
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LI Fu-lin, ZHANG Qi-kai. MOLECULAR CONNECTIVITY IN QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS STUDY OF GANGLION BLOCKING AGENTS OF ALIPHATIC AMINESJ. Acta Pharmaceutica Sinica, 1982, 17(8): 592-596.
Citation: LI Fu-lin, ZHANG Qi-kai. MOLECULAR CONNECTIVITY IN QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS STUDY OF GANGLION BLOCKING AGENTS OF ALIPHATIC AMINESJ. Acta Pharmaceutica Sinica, 1982, 17(8): 592-596.
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分子连接性在脂肪胺类神经节阻断剂定量构效关系中的应用

MOLECULAR CONNECTIVITY IN QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS STUDY OF GANGLION BLOCKING AGENTS OF ALIPHATIC AMINES

    摘要
  • 摘要: 用分子连接性探讨了一系列正丙胺衍生物的定量构效关系,90%以上的神经节阻断作用活性变异可以用建立起来的方程解释。

     

    Abstract: The quantitative structure activity relationships of a series of ganglion blocking n-propylamine derivatives were examined using molecular connectivity analysis. Greater than 90% of the variance in activity as ganglion blocking agents can be explained on this basis.

     

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