二阶导数光谱法测定酮洛芬体外经皮渗透量

胡晋红, 朱宇, 薛佩华. 二阶导数光谱法测定酮洛芬体外经皮渗透量J. 药学学报, 1997, 32(7): 542-545.

引用本文:

胡晋红, 朱宇, 薛佩华. 二阶导数光谱法测定酮洛芬体外经皮渗透量J. 药学学报, 1997, 32(7): 542-545.

JH Hu, Y Zhu , PH Xue, . DETERMINATION OF PERMEATION OF KEJ. Acta Pharmaceutica Sinica, 1997, 32(7): 542-545.

Citation:

JH Hu, Y Zhu , PH Xue, . DETERMINATION OF PERMEATION OF KEJ. Acta Pharmaceutica Sinica, 1997, 32(7): 542-545.

DETERMINATION OF PERMEATION OF KE

摘要: 为进一步探讨酮洛芬透皮给药的可行性,用二阶导数光谱法测定酮洛芬体外经皮渗透量。结果表明,本法可排除皮下组织的干扰,能准确测定药物体外渗透量,且操作简便、快速。平均回收率为99.00%±1.51%。

Abstract: A second order derivative spectrophotometric method was developed for the permeative determination of ketoprofen in vitro. The method can avoid the disturbance of skin tissue. The procedure is simple and rapid. The results are accurate.The mean recovery of ketoprofen is 99.00%±1.51%.

/