白花败酱草化学成分的分离与结构鉴定

Isolation and structure identification of chemical constituents from Patrinia villosa

摘要: 目的研究白花败酱草的化学成分。方法利用溶剂萃取后进行硅胶柱和制备液相色谱分离纯化，根据理化性质和光谱数据鉴定结构。结果分离并鉴定了8个化合物：bolusanthol B (1)，(2S)-5,7,2′,6′-四羟基-6,8-二异戊烯基-二氢黄酮(2)，orotinin (3)，(2S)-5,7,2′,6′-四羟基-6-lavandulyl-二氢黄酮(4)，3′-异戊烯基-芹黄素(5)，木犀草素(6)，槲皮素(7)和洋芹素(8)。结论化合物2，4为新化合物，1，3，5为首次从败酱属植物中分离得到，6，7，8为首次从白花败酱草中分离得到。

Abstract: AimTo study the chemical constituents of Patrinia villosa Juss. MethodsSolvent extraction, silica gel column and preparative liquid chromatography were used to separate the chemical constituents, and the chemical structures were elucidated by physico-chemical properties and spectra data. ResultsEight compounds were isolated and identified as bolusanthol B (1), (2S)-5,7,2′,6′-tetrahydroxy-6,8-di (γ,γ-dimethylallyl) flavanone (2), orotinin (3), (2S)-5, 7, 2′, 6′-tetrahydroxy-6-lavandulylated flavanone (4), 3′-prenyl-apigenine (5), luteolin (6), quercetin (7) and apigenin (8). ConclusionCompound 2 and 4 are new compounds, compounds 1, 3 and 5 were separated from Patrinia genius for the first time, compounds 6, 7 and 8 were isolated from Patrinia vollosa Juss for the first time.