谭桂山, 徐康平, 徐平声, 胡高云, 李元建. 川东獐牙菜化学成分研究J. 药学学报, 2002, 37(8): 630-632.
引用本文: 谭桂山, 徐康平, 徐平声, 胡高云, 李元建. 川东獐牙菜化学成分研究J. 药学学报, 2002, 37(8): 630-632.
TAN Gui-shan, XU Kang-ping, XU Ping-sheng, HU Gao-yun, LI Yuan-jian. STUDIES ON THE CHEMICAL CONSTITUENTS OF SWERTIA DAVIDA FRANCHJ. Acta Pharmaceutica Sinica, 2002, 37(8): 630-632.
Citation: TAN Gui-shan, XU Kang-ping, XU Ping-sheng, HU Gao-yun, LI Yuan-jian. STUDIES ON THE CHEMICAL CONSTITUENTS OF SWERTIA DAVIDA FRANCHJ. Acta Pharmaceutica Sinica, 2002, 37(8): 630-632.

川东獐牙菜化学成分研究

STUDIES ON THE CHEMICAL CONSTITUENTS OF SWERTIA DAVIDA FRANCH

  • 摘要: 目的研究川东獐牙菜(Swertia davidi Franch)活性成分。方法用硅胶色谱技术分离化学成分,用UV,IR,NMR和MS等光谱方法鉴定化合物。结果得到3个化合物,分别鉴定为:1,7-二羟基-3,8-二甲氧基酮(V);1,8-二羟基-3,7-二甲氧基酮(VI)和1,8-二羟基-3,4,7-三甲氧基酮(VII)。结论VII为新酮,其余两个酮均首次从该植物中分离得到。

     

    Abstract: AIMTo study the active constituents of Swertia davidi Franch.. METHODSChromatography was used to isolate and purify the chemical components, their structures were identified by spectral analysis. RESULTS Three compounds were identified as 1,7-dihydroxy-3,8-dimethoxyxanthone (gentiacaulein) (V), 1,8-dihydroxy-3,7-dimethoxyxanthone (methylswertianin) (VI) and 1,8-dihydroxy-3,4,7-trimethoxyxanthone (VII). CONCLUSION Compound VII is a novel xanthone, named daviditin A, the others were isolated from Swertia davidi Franch. for the first time.

     

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