刘燕, 王志尧, 贺文军, 谭宁华, 殷志琦. 小芸木茎和叶中化学成分研究J. 药学学报, 2015,50(4): 475-479.
引用本文: 刘燕, 王志尧, 贺文军, 谭宁华, 殷志琦. 小芸木茎和叶中化学成分研究J. 药学学报, 2015,50(4): 475-479.
LIU Yan, WANG Zhi-yao, HE Wen-jun, TAN Ning-hua, YIN Zhi-qi. Chemical constituents from stems and leaves of Micromelum integerrimumJ. Acta Pharmaceutica Sinica, 2015,50(4): 475-479.
Citation: LIU Yan, WANG Zhi-yao, HE Wen-jun, TAN Ning-hua, YIN Zhi-qi. Chemical constituents from stems and leaves of Micromelum integerrimumJ. Acta Pharmaceutica Sinica, 2015,50(4): 475-479.

小芸木茎和叶中化学成分研究

Chemical constituents from stems and leaves of Micromelum integerrimum

  • 摘要: 通过硅胶、凝胶、RP-18 和HPLC 等一系列色谱方法对小芸木茎和叶中化学成分进行研究,得到8 个化合物,包括两个新化合物(12)和6 个已知化合物(38).通过一维、二维核磁共振以及高分辨质谱等波谱数据对这些化合物进行结构鉴定,其中化合物microintegerrin C(1)为一个新的苯环衍生物,化合物microintegerrinD(2)为一个新的降倍半萜,化合物38 为首次从该植物中分离得到.

     

    Abstract: A new benzene derivative microintegerrin C (1) and a new norsesquiterpenoid microintegerrin D (2), along with six known compounds (3-8), were isolated and identified from stems and leaves of Micromelum integerrimum by various chromatographies such as silica gel, Sephadex LH-20, RP-18 column chromatography and HPLC. Their structures were mainly identified based on the spectral data analysis such as 1D-, 2D-NMR and HR-EI-MS. All known compounds were isolated from this plant for the first time.

     

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