从平贝母茎叶中分离的平贝啶甙的结构

STRUCTURE OF PINGBEIDINOSIDE,AN ALKALOID ISOLATED FROM THE STEMS AND LEAVES OF FRITILLARIA USSURIENSIS MAXIM

摘要: 本文报道自平贝母(Fritillaria ussuriensis Maxim)的地上茎叶中分得一种新的甾体生物碱甙,定名为平贝啶甙(pingbeidinoside),mp 242～243.2℃a_D²⁵+6.9°(c 0.145,MeOH)。经IR,MS,¹HNMR和¹³CNMR谱解析,推定其结构为3β,16α,20-三羟基-Δ⁵-22,26-缩亚胺胆甾烷-25-O-α-D-葡萄糖甙。

Abstract: A new steroid alkaloid glucoside,pingbeidinoside,was isolated from the stem and leaf of Fritillaria ussuriensis Maxim by column chromatographic techniques. On the basis of the IR, MS, ¹HNMR and ¹³CNMR spectra of pingpeidinoside and products of its transfomation, the structure of pingbeidinoside has been established as 3β,16α,20-trihydroxy-△⁵-22,26-epiminocholestane-25-O-β-D-glucoside.