中药泥胡菜化学成分的研究

STUDY ON CHEMICAL CONSTITUENTS OF HEMISTEPTA LYRATA BUNGE

摘要: 目的　研究泥胡菜(Hemistepta lyrata Bunge .)全草化学成分。方法　采用现代色谱技术分离化合物,用化学方法和现代波谱技术(UV ,IR ,EIMS ,FABMS ,ESIMS ,¹HNMR ,¹³CNMR ,HMQC ,HMBC)鉴定化合物的结构。结果　从中药泥胡菜全草的乙醇提取物中分离得到5个化合物,分别鉴定为芹菜素(apigenin ,I) ,芹菜素-7-O-β-D-芦丁糖苷(apigenin-7-O-β-D-lutinoside ,II) ,金合欢素-7-O-β-D-芦丁糖苷(acacetin-7-O-β-D-lutinoside ,III) ,紫云英苷(astragalin ,IV)和泥胡木烯苷(hemislienoside ,V)。结论　化合物V为新化合物,化合物I-IV为首次从该植物中分离得到

Abstract: AIM To separate and identify the chemical constituents of the whole plant of Hemistepta lyrata Bunge. METHODS Compounds wese separated with chromatography and their chemical strucrures were elucidated with UV, IR, EIMS, FABMS, ESIMS, ¹HNMR, ¹³CNMR HMQC and HMBC spectral methods. RESULTS Five compounds were isolated from the plant. They were identified as apigenin I, apigenin-7-O-β-D-lutinoside II, acacetin-7-O-β-D-lutinoside III, astragalin IV, hemislienoside V. CONCLUSION These compounds were isolated from this plant for the first time, and compound V is a new one.