利国威, 潘启超, 杨小平, 应百平. 短刺虎刺中8-羟基虎刺素-ω-乙基醚的分离和结构鉴定J. 药学学报, 1984, 19(9): 681-685.
引用本文: 利国威, 潘启超, 杨小平, 应百平. 短刺虎刺中8-羟基虎刺素-ω-乙基醚的分离和结构鉴定J. 药学学报, 1984, 19(9): 681-685.
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LI Guo-Wei, PAN Qi-Chao, YANG Xiao-Ping , YING Bai-Ping, . ISOLATION AND STRUCTURAL DETERMINATION OF 8-HYDROXY DAMNACANTHOL-ω-ETHYL ETHER FROM THE ROOT OF DAMNACANTHUS SUBSPINOSUS HAND-MAZZJ. Acta Pharmaceutica Sinica, 1984, 19(9): 681-685.
Citation: LI Guo-Wei, PAN Qi-Chao, YANG Xiao-Ping , YING Bai-Ping, . ISOLATION AND STRUCTURAL DETERMINATION OF 8-HYDROXY DAMNACANTHOL-ω-ETHYL ETHER FROM THE ROOT OF DAMNACANTHUS SUBSPINOSUS HAND-MAZZJ. Acta Pharmaceutica Sinica, 1984, 19(9): 681-685.
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短刺虎刺中8-羟基虎刺素-ω-乙基醚的分离和结构鉴定

ISOLATION AND STRUCTURAL DETERMINATION OF 8-HYDROXY DAMNACANTHOL-ω-ETHYL ETHER FROM THE ROOT OF DAMNACANTHUS SUBSPINOSUS HAND-MAZZ

    摘要
  • 摘要: 从短刺虎刺(Damnacanthus subspinosus Hand-Mazz)的根中分得一新蒽醌化合物,经光谱分析推定其结构为1-甲氧基-2-乙氧甲基-3,8-二羟基蒽醌,命名为8-羟基虎刺素-ω-乙基醚(8-Hydroxydamnacanthol-ω-ethyl ether)。对Hela细胞体外培养有一定抑制作用。

     

    Abstract: The structure of a new anthraquinone isolated from the root of Damnacanthus subspinosus Hand-Mazz (Rubiaceae) was found to be 3,8-dihydroxy2-ethoxymethyl-1-methoxyanthraquinone Ⅳ by means of NMR, IR, UV and MS analyses. This anthraquinone is named 8-hydroxydamnacanthol-ω-ethyl ether. The compound was found to be active against Hela cells in culture.

     

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