毛叶香茶菜抗癌成分的研究——Ⅱ.毛叶香茶菜素E的结构

STUDIES ON THE ANTITUMOR DITERPENOID CONSTITUENTS OF RABDOSIA JAPONICA (BURM.F) HARA Ⅱ. THE STRUCTURES OF RABDOSIN C

摘要: 从Rabdosia japonica(Burm.f)Hara中又分得四种二萜,经化学和光谱数据确定其中三个为已知的Epinodosin(Ⅰ)、Lasiokaurin(Ⅱ)和Oridonin(Ⅲ)。而另一二萜为首次从植物中分得的天然产物,命名为Rabdosin C,其化学结构用(Ⅵ)式表示。

Abstract: Rabdosin C, a new diterpenoid having a B-seco-ent-(—)-Kaurene skeleton, and three diterpenoids, Epinodosin (Ⅰ), Lasiokaurin (Ⅱ) and Oridonin (Ⅲ), have been isolated from the ethereal extract of the leaves of Rabdosia japonica (Burm. f) Hara (Labiatae) collected in Henan.On the basis of chemical and spectroscopic data, the chemical structures of Rabdosin C was established as (Ⅵ).