海藻中两种新化学成分的分离和结构鉴定

ISOLATION AND IDENTIFICATION OF TWO NEW CONSTITUENTS FROM ALGAE

摘要: 目的：研究中国南海褐藻Sargassum vachellianum和绿藻Ulva lactuca的化学成分。方法：应用各种色谱技术进行分离纯化，用MS，IR，¹HNMR，¹³CNMR（DEPT），HMQC和HMBC鉴定化合物。结果：分离并鉴定了2个新化合物，化合物1 vachellin为11-甲基-Δ^1，5-3，7，10-三羰基-2，4，8，9-四氮-环十一二烯，化合物2 lactucasterol为胆甾-28-甲基-23,24-环丙烷-Δ⁵-4-酮。结论：1和2为新化合物。

Abstract: AIM：To study the chemical composition in the alga Sargassum vachellianum and Ulva lactua collected from South China Sea. METHODS: Various column chromatography were used to separate the chemical constituents. MS, IR, ¹HNMR, ¹³CNMR（DEPT）, HMQC and HMBC were used to determine the structure of the isolated constituent. RESULTS: Two new compounds were isolated and their structure were elucidated as 11-methyl-1,5-diene-3,7,10-tricarbonyl-2,4,8,9-tetranitrogen-cycloundecandien(1) and cholesta-28-methyl-23,24-cyclopropane-Δ⁵-4-one-3β-ol(2) on the basis of spectral evidence. CONCLUSION: compounds 1 and 2 are new compounds.