肿瘤的化学治疗 Ⅺ.几种α-酮醛类及苯骈对氮六环的衍生物的合成
TUMOUR CHEMOTHERAPY Ⅺ.SYNTHESIS OF SOME α-KETOALDEHYDES AND QUINOXALINES
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摘要: 1.本文合成了几种芳香族的a-酮醛类化合物及苯骈对氮六环的衍生物。2.合成的化合物部分通过体外试验,部分经过动物筛选,均无明显的抗肿瘤作用。Abstract: Recent reports on antiviral compounds with α,β-dicarbonyl structure led us to prepare a number of aromatic α-ketoaldehydes (Ⅳ) and their corresponding quinoxaline derivatives (Ⅴ) for screening in experimental tumours. All of the compounds showed no inhibitory action against sarcoma 180 or Ehrlich carcinoma.
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