山野豌豆黄酮类化学成分的研究

STUDIES ON THE CHEMICAL CONSTITUTENS OF VICIA AMOENA FISCH

摘要: 自山野豌豆(Vicia amoena Fisch.)全草的乙醇提取物中分得6个化合物,经波谱和化学分析鉴定其中一个为新的黄酮甙,命名为山野豌豆甙(amoenin A₃),其余5个化合物为槲皮素(quercetin D₂)、山奈酚(kaempferol D₁)、槲皮素-3-O-α-L-鼠李糖甙(quercetin-3-O-α-L-rhamnosideC1)、槲皮素-3-O-β-D-葡萄糖甙(quercetin-3-O-β-D-glucosideC2)、山柰酚-3,7-O-α-L-二鼠李糖甙(kaempferol-3,7-O-α-L-dirhamnoside A₂)。以上黄酮类化合物均为首次从山野豌豆中分得。

Abstract: One new flavonoide was isolated from Vicia amoena Fisch. On the basis of spectral(UV,MS,NMR)and chemical reactions, it was elucidated to be kaempferol-3-O-β-D-mannoside, named amoenin(A₃). Moreover, five known compounds have been isolated and identified as quercetin, kaempferol, quercetin-3-O-α-L-rhamoside, quercetin3-O-β-D-glucoside, kaempferol-3,7-O-α-L-dirhamoside. The total flavonoides showed significant effects on inducing hyperlipidemia and increasing micro-blood vessel elasticity.