沙苑子有效成分的研究

STUDIES ON THE EFFICACIOUS CONSTITUENTS OF ASTRAGALUS COMPLANATUS

摘要: 沙苑子(Astragalus complanatus R.Br.)甲醇提出物的石油醚溶出部位显示较强降转氨酶活性,从此部位分得6个单体,经理化常数测定和光谱解析证明为:鼠李柠檬素(I),芒柄花素(II),豆甾醇(IV),磷脂酰乙醇胺(V),磷脂酰肌醇(VI)和新化合物11-O-p-coumarylnepeticin(II),以上化合物均为首次从该植物中得到。

Abstract: The petroleum ether extract of Astragalus complanatus R.Br. showed activity for lowering the transaminase levels in mice. From this extract six compounds were isolated. Among them five were identified as rhamnocitrin (I), formononetin (II), stigmasterol (IV), phosphatidylethanolamine (V) and phosphatidylinositol (VI). The other one was shown to be a new p-coumaroyl derivative, 11-O-p-coumarylnepeticin. Their structures were elucidated by spectrometric and chemical analyses. All the six compounds were isolated from this plant for the first time.