顾学裘, 沈文照, 陈瑞龙, 郦章安. 中药白及的研究 (二)白及膠质作为片剂赋形剂的研究J. 药学学报, 1955, 3(3): 257-266.
引用本文: 顾学裘, 沈文照, 陈瑞龙, 郦章安. 中药白及的研究 (二)白及膠质作为片剂赋形剂的研究J. 药学学报, 1955, 3(3): 257-266.
KOO HSUEH-CHIU SHEN WEN-CHAO CHEN SHUI-LUNG LI CHANG-AN, . A STUDY OF THE CHINESE DRUG “BAI-GI”(Ⅱ)THE EVALUATION OF THE MUCILAGE OF BLETILLA STRIAT AS BINDING AGENT IN TABLET MAKINGJ. Acta Pharmaceutica Sinica, 1955, 3(3): 257-266.
Citation: KOO HSUEH-CHIU SHEN WEN-CHAO CHEN SHUI-LUNG LI CHANG-AN, . A STUDY OF THE CHINESE DRUG “BAI-GI”(Ⅱ)THE EVALUATION OF THE MUCILAGE OF BLETILLA STRIAT AS BINDING AGENT IN TABLET MAKINGJ. Acta Pharmaceutica Sinica, 1955, 3(3): 257-266.

中药白及的研究 (二)白及膠质作为片剂赋形剂的研究

A STUDY OF THE CHINESE DRUG “BAI-GI”(Ⅱ)THE EVALUATION OF THE MUCILAGE OF BLETILLA STRIAT AS BINDING AGENT IN TABLET MAKING

  • Abstract: (1)In the previous studies of the Chinese drug “Bai-Gi”,the rhizomes of Bletilla striata,the mucilage extracted from it was investigated with re- ference to:(a) the method of its extraction,(b) the apparent viscosity and the su- spending power as compared with the mucilages of acacia and tragacanth under the same condition,and (c) the emulsifying properties as measured by means of the globules-counting method and the degree of creaming. (2)In the present investigation,studies have been made to compare the cohesive properties of the three tablet binders including (a)10% starch paste, (b)15% Acacia mucilage,and (c)2% mucilage of Bletilla striata employed in the granulating process for four kinds of tablets namely,lactose-starch,sul- fathiazole,sodium bicarbonate and aluminum hydroxide. (3)The determination of hardness,weight variations and disintegration time of the tablets of various medicinals granulated with 2% mucilage of Bletilla striata gave favorable results,as compared with those of the tablets of the same medicinals granulated with 10% starch paste and 15% mucilage of acacia.

     

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