茜草中萘酸酯类成分的研究

STUDIES ON NAPHTHOIC ACID ESTERS FROM THE ROOTS OF RUBIA CORDIFOLIA L.

摘要: 从茜草根中分离出四个萘酸甲酯化合物。经光谱分析及化学方法鉴定,化合物Ⅰ为一新成分,命名为茜草内酯(rubilactone,Ⅰ),化合物Ⅱ～Ⅳ分别为已知物3’-甲氧羰基-4’-羟基-萘骈1’,2’-2,3呋喃(furomollugin,Ⅱ),二氢大叶茜草素(dihydromollugin,Ⅲ),2-(3’-羟基)异戊基-3-甲氧羰基-1,4-萘氢醌-1-O-β-D-吡喃葡萄糖甙(Ⅳ)。其中Ⅱ系自茜草属中首次分得。

Abstract: Four naphthoic acid esters including a new compound were isolatedfrom the roots of Rubia cordifolia L.. The new one was named as rubilactone and its struc-ture was elucidated as 3'-carbomethoxy-4'-hydroxy-naphtho1',2'-2,3 pyran-6-one(I) based on the physicochemical properties and spectrometric analyses (UV, IR, MS,¹HNMR and ¹³CNMR). The other three were 3'-carbomethoxy-4'-hydroxy-naphtho 1',2'-2, 3 furan (Ⅱ), dihydromollugin (Ⅲ) and 3-carbomethoxy-2-(3'-hydroxy)isopentyl-1,4-naphthohydroquinone- 1- O-β- D-glucoside(Ⅳ).