银杏叶中的黄酮醇苷类成分

FLAVONOL GLYCOSIDES FROM THE LEAVES OF GINKGO BILOBA

摘要: 目的　对银杏（Ginkgo biloba L.）叶的化学成分进行分离、鉴定。方法　采用各种色谱技术进行分离，用IR,UV,MS,¹HNMR,¹³CNMR和2DNMR光谱技术确定化合物的结构。结果　分得8个黄酮醇苷类成分：槲皮素-3-O-β-D-葡糖苷（1），山奈酚-3-O-β-D-葡糖苷（2），芦丁（3），山奈酚-3-O-β-D-芸香糖苷（4），异鼠李素-3-O-β-D-芸香糖苷（5），槲皮素-3-O-β-D-葡萄糖基(1-2)-α-L-鼠李糖苷（6），山奈酚-3-O-β-D-葡萄糖基(1-2)-α-L-鼠李糖苷（7），异鼠李素-3-O-β-D-葡萄糖基(1-2)-α-L-鼠李糖苷（8）。结论　化合物8为新化合物。

Abstract: AIM　Isolation and structural elucidation of the constituents from leaves of Ginkgo biloba. METHODS　To isolate chemical constituents, solvent extraction together with column chromatography was used. IR, UV, MS and NMR spectra were employed for structural identification. RESULTS　Eight flavonol glycosides were isolated. They were elucidated as quercetin-3-O-β-D-glucoside(1), kaempferol-3-O-β-D-glucoside(2), rutin(3), kaempferol-3-O-β-D-rutinoside(4), isorhamnetin-3-O-β-D-rutinoside(5), quercetin-3-O-β-D-glucosyl(1-2)-α-L-rhamnoside(6), kaempferol-3-O-β-D-glucosyl(1-2)-α-L-rhamnoside(7) and isorhamnetin-3-O-β-D-glucosyl(1-2)-α-L-rhamnoside(8). CONCLUSION　Compound 8 was shown to be a new compound.