柴胡皂甙m和柴胡皂甙n的结构鉴定

THE STRUCTURES OF SAIKOSAPONIN M AND N FROM BUPLEURUM SMITHII WOLFF

摘要: 从黑柴胡(Bupleurum smithii Wolff)根中分得二个新三萜皂甙。根据理化性质和波谱数据,分别鉴定为3β,23,28-三羟基齐墩果烷-11,13(18)-二烯-3-O-β-D-吡喃葡萄糖基-(1→3)-β-D-吡喃呋糖甙,命名为柴胡皂甙m(saikosaponin m,IV),和3β,16β,23,28-四羟基齐墩果烷-11,13(18)-二烯-3-O-β-D-吡喃葡萄糖基-(1→6)-α-L-吡喃鼠李糖基-(1→4)-β-D-吡喃葡萄糖甙,命名为柴胡皂甙n(saikos-aponinn,IX)。

Abstract: From the roots of Bupleurum Smithii Wolff, collected in Minhe County,Qinghai,China,two new saikosaponins were isolated and their structures were elucidated on the basis of spectralanalysis of UV,IR,¹HNMR,¹³CNMR and FAB-MS.The two new saponins named as saikosaponinm and saikosaponin n,were identified as 3β,23,28-trihydroxyoleana-11,13(18)-dien-3-O-β-D-glu-copyranosyl-(1→3)-β-D-fucopyranoside and 3β,16β,23,28-tetrahydroxyoleana-11, 13(18)-dien-3-O-β-D-glucopyranosyl-(1→6)-α-L-rhamnopyranosyl(1→4)-β-D-glucopyranoside,respectively.