蒋亭, 田黎, 郭爱华, 付宏征, 裴月湖, 林文翰. 黄海葵附生真菌Penicillium thomii的化学成分J. 药学学报, 2002, 37(4): 271-274.
引用本文: 蒋亭, 田黎, 郭爱华, 付宏征, 裴月湖, 林文翰. 黄海葵附生真菌Penicillium thomii的化学成分J. 药学学报, 2002, 37(4): 271-274.
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JIANG Ting, TIAN Li, GUO Ai-hua, FU Hong-zheng, PEI Yue-hu, LIN Wen-han. CHEMICAL CONSTITUENTS FROM MARINE FUNGUS PENICILLIUM THOMIIJ. Acta Pharmaceutica Sinica, 2002, 37(4): 271-274.
Citation: JIANG Ting, TIAN Li, GUO Ai-hua, FU Hong-zheng, PEI Yue-hu, LIN Wen-han. CHEMICAL CONSTITUENTS FROM MARINE FUNGUS PENICILLIUM THOMIIJ. Acta Pharmaceutica Sinica, 2002, 37(4): 271-274.
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黄海葵附生真菌Penicillium thomii的化学成分

CHEMICAL CONSTITUENTS FROM MARINE FUNGUS PENICILLIUM THOMII

    摘要
  • 摘要: 目的研究黄海葵(anemone)附生真菌Penicillium thomii的化学成分。方法用各种色谱技术进行分离纯化,根据理化性质和波谱数据进行结构鉴定。结果从黄海葵附生真菌Penicillium thomii菌丝体中分离得到5个化合物,分别为青霉酮A(I),对甲基苯甲酸(II),1-O-十六碳烷酰-2-O-(9-十八碳烯酰)-3-O-(9,12-十八碳二烯酰)甘油酯(III),5α,8α-环二氧-24ζ-甲基胆甾-6,22-二烯-3β-醇(IV)和大黄素(V)。结论青霉酮A(I)为新化合物,化合物II,III,IV和V系首次从该属中分离得到。

     

    Abstract: AIMTo investigate the bioactive constituents from the mycelium of Penicillium thomii. Which isolated from Anemone collected in Qingdao beach. METHODSThe constituents were separated by using various chromatography and the structures were identified on the basis of extensive spectral analysis. RESULTSFive compounds, namely penicillixanthone A (I), p-methylbenzolic acid (II), 1-O-hexadecanoyl-2-O-(9-octadecenoyl)-3-O-(9,12-octadecadienoyl) glycerol (III), 5α,8α-epidioxy-24ζ-methylcholesta-6,22-dien-3β-ol (IV) and 1,6,8-trihydroxyl-3-methyl-9,10-anthracenedione (V), were isolated from the mycelium of Penicillium thomii. CONCLUSIONPenicillixanthone A is a new compound, while the others are isolated from Penicillium thomii for the first time.

     

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