Abstract: The pharmacological action of the bulb of Lycoris radiata Herb. is commonly known as an emetic and an expectorant. In this report, the authors further investigated the stimulating action on uterus and found Lycoris radiata Herb. acted very much like ergot. Moreover, when the decoction made from 1 gm of this drag was injected intramuscularly into a rooster's breast, the tip of the comb became blue after 1(1/2) hours. The decoction of Lycoris radiata Herb. stimulated the isolated rabbit ileum, and caused emesis in pigeons. On isolated guinea pig's uterus, the decoction of Lycoris radiata Herb. was not antagonized by benadryl. The authors suggest that it might be a good substitute for ergot preparations.