Abstract: A new diterpenoid quinone, named sapriparaquinone (1) was isolated from the root of Salvia prionitis Hance. 1 was identified as 3-hy-droxy-6-methyl-2-(1-methyl)-5-(4-methylpenten-3-yl)-1, 4-naphthoquinone by spectral analysis and chemical transformation of saprorthquinone (2). 1 and 2 are 4,5-seco-5, 10-frideoabietane derivatives and must be biogenetically derived from an abietane structure. Like 2, 1 also showed cytotoxieity against P388 leukemia cells.