黄花远志根化学成分的分离和结构鉴定

STUDIES ON CHEMICAL CONSTITUENTS OF POLYGALA ARILLATA BUCH-HAM

摘要: 从黄花远志(Polygala arilata Buch-Ham.)根中分离得到7个化合物,根据光谱(UV,IR,MS,¹HNMR,DIFNOE和¹³CNMR)解析和理化性质,分别鉴定为1-甲氧基-2,3-亚甲二氧基口山酮(I)、1,7-二羟基-2,3-亚甲二氧基口山酮(II)、1,6,7-三羟基-2,3-二甲氧基口山酮(II)、对羟基苯甲酸(IV)、远志醇(V)、豆甾醇(VI)、豆甾醇β-D-吡喃葡萄糖甙(VII)。其中,I和II为新化合物,VI和VI为首次从该植物中分得。化合物I～II有抑制醛糖酶的作用。

Abstract: Seven compounds were isolated from the roots of Polyyala arillata Buch-Ham. Onbasis of chemical reactions and spectral (UV) IR ,MS,¹HNMR,DIFNoE,¹³CNMR)analysis, theywere identified as 1-methoxy-2,3-methylenedioxyxanthone(I),1,7-dihydroxy-2,3-methylene-dioxyxanthone(II),1,6,7-trihydroxy-2,3-dimethoxyxanthone(III),p-hydroxy-benzoic acid(IV),polygalitol(V),stigmasterol(VI)and stigmasterol-3-O-β-D-glucopyranoside(VII).II and IIIare new compounds.Pharmacological study indicated that I,Il and III inhibit aldose reductase.