卷柏化学成分研究卷柏化学成分研究

Study on the chemical constituents of Selaginella tamariscina (Beauv.) Spring

摘要: 目的研究中药卷柏(Selaginella tamariscina (Beauv.) Spring)水提物中的化学成分。方法利用Sephadex LH-20及硅胶等色谱技术进行分离纯化,根据理化性质、光谱数据进行结构鉴定。结果得到4个化合物,分别鉴定为1-羟基-2-［2-羟基-3-甲氧基-5-(1-羟基乙基)-苯基］-3-(4-羟基-3,5-二甲氧基苯基)-丙烷-1-O-β-D-葡糖苷(卷柏苷B,I),腺苷(II),鸟苷(III),熊果苷(IV)。结论卷柏苷B为新化合物,腺苷、熊果苷、鸟苷为首次从卷柏属植物中分离得到。

Abstract: AimTo study the chemical constituents of Selaginella tamariscina (Beauv.) Spring. MethodsVarious chromatographic techniques were used to separate and purify the chemical constituents. Their physico-chemical properties and spectral data were used to elucidate the structures. ResultsFour compounds were isolated from the n-BuOH fraction of the water-extracts. Their structures were identified as 1-hydroxy-2-［2-hydroxy-3-methoxy-5-(1-hydroxyethyl)-phenyl］-3-(4-hydroxy-3,5-dimethoxy)-propane-1-O-β-D-glucopyranoside (tamariscinoside B, I), adenosine (II), guanosine (III), arbutin (IV). Conclusion Tamariscinoside B (I) is a new compound, while the others were isolated from Selaginella for the first time.