杨彤彤 李静 秦民坚 赵明 欧阳臻 付海珍. 补骨脂中两个新的黄酮类化合物J. 药学学报, 2009,44(12): 1387-1390.
引用本文: 杨彤彤 李静 秦民坚 赵明 欧阳臻 付海珍. 补骨脂中两个新的黄酮类化合物J. 药学学报, 2009,44(12): 1387-1390.
YANG Tong-Tong, LI Jing, QIN Min-Jian, DIAO Meng, OU Yang-Zhen, FU Hai-Zhen. Two new compounds from Psoralea corylifolia L.J. 药学学报, 2009,44(12): 1387-1390.
Citation: YANG Tong-Tong, LI Jing, QIN Min-Jian, DIAO Meng, OU Yang-Zhen, FU Hai-Zhen. Two new compounds from Psoralea corylifolia L.J. 药学学报, 2009,44(12): 1387-1390.

补骨脂中两个新的黄酮类化合物

Two new compounds from Psoralea corylifolia L.

  • 摘要:

    为了研究补骨脂的化学成分, 采用色谱法分离化合物, 根据理化性质和光谱数据鉴定化合物结构。分离鉴定了2个化合物: 2-(3, 4-二羟基)苯基-8, 8-二甲基-8H-吡喃骈2, 3-h色烯-4- (1) 5-(1-甲基-2-羟基)乙基-4, 5-二氢呋喃2, 3-h (4'-羟基-3', 5'-二甲氧基)-异黄酮 (2)。化合物12均为新化合物, 分别命名为补骨脂色烯黄酮 (coryfolia D) 和补骨脂新异黄酮 (bavarigenin)

     

    Abstract:

    To study the chemical constituents of the fruits of Psoralea corylifolia L., the constituents were isolated and purified by chromatography.  Two new compounds were isolated from the ethyl acetate-soluble fraction of the ethanol extract.  On the basis of chemical and spectroscopic data 1D and 2D NMR, they were identified as 2-(3, 4-dihydroxyphenyl)-8, 8-dimethyl-8H-pyrano2, 3-hchromen-4-one (1) and 5-(2-hydroxyl-1- methyl)-ethyl-4, 5-dihydrofurano2, 3-h(4'-hydroxyl-3', 5'-dimethoxy)-isoflavone (2), and named as coryfolia D and bavarigenin separately.

     

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