蛇足石杉生物碱成分的研究

STUDIES ON THE ALKALOIDS OF HUPERZIA SERRATA (THUNB.) TREV.

摘要: 从石杉科植物蛇足石杉中分离出三个生物碱(Ⅰ～Ⅲ)。经光谱数据和衍生物的制备证明:生物碱(Ⅰ)和(Ⅲ)分别为石杉碱乙(Ⅰ)和N-甲基石杉碱乙(Ⅲ);生物碱(Ⅱ)为新化合物,命名为蛇足石杉碱(huperzinine)。本文报告碱(Ⅱ)的结构测定。(Ⅱ)的生物活性正在研究中。

Abstract: Three alkaloids were isolated from Huperzia serrata (Tunb.) Trev. Two of them were identified as known alkaloids huperzine B(Ⅰ) and N-methyl huperzine B(Ⅲ), respectively. The third alkaloid Ⅱ was found to be a new compound named huperzinine. Its structure was confirmed on the basis of chemical and spectral data (UV, IR, NMR, MS).